Case Study: Cancer Patient with Epidermolysis Bullosa (EB)

A 46 year old female suffered from epidermolysis bullosa (EB) on her feet due to her chemotherapy. The patient was suffering from ovary cancer and receiving chemotherapy. 

The wounds were initially treated with topical antibiotics and foam dressings to provide an occlusive environment. The medications barely worked.

The medical professionals decided to switch to medical grade honey-based wound dressings with the expectation that debridement and angiogenesis could be stimulated.

The wounds on both feet were dressed daily with a thin layer of L-Mesitran ointment, covered with an occlusive foam dressing. Dressing was changed once per day during the first week, after which the frequency was lowered.

The wounds on the left foot covered an area of approximately 8x4cm and on the right foot,11×4 cm. Within 4 days, the wound started to debride and granulation tissue was seen. The left foot healed in 10 days and the small wound on the right foot healed completely within 17 days. 

The patient reported some sensation but not pain during the application or at dressing changes. No adverse effects were observed.