Healing a Chronic Wound: The Journey of an 85-Year-Old Man’s Little Toe

Products: L-Mesitran Soft
Case study performed by: Daniela Chrysostomou, Wound Clinic Health@45, Johannesburg, South Africa.

An 85-year-old male patient came to the clinic with a wound on his right little toe caused by an impact injury three months earlier. He also had other wounds due to lymphedema, which were being treated by a specialist. The patient had numerous health issues, including hypertension, dry skin, digestive problems, arthritis, prostate cancer, kidney inflammation, reduced lung capacity, thyroid dysfunction, Parkinson’s disease, gout, neuropathy, anemia, and a cardiac valve replacement two years prior. Despite previous treatments with silver alginate and silicone with silver, the toe wound remained unhealed, prompting a switch to medical-grade honey (MGH).

Method: The wound was cleaned with chlorhexidine and then treated with L-Mesitran Soft, a medical-grade honey ointment, and covered with silicone foam. This routine was followed twice a week to stabilize the toe and promote healing.

Results: At the beginning of treatment, the wound exhibited low exudate, necrosis, slough, odor, and macerated edges, and was infected with Proteus mirabilis and Enterococcus faecalis. Systemic antibiotics (Augmentin 1g twice daily for 5 days) were prescribed based on sensitivity testing. The L-Mesitran Soft dressings facilitated good wound cleansing, allowing for sharp debridement after three days. A month into the treatment, a small piece of loose bone was removed, causing minor bleeding, but the healing continued without interruption. The wound was completely healed after three months.

Toe 2
Toe wounds over time
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Discussion: The treatment with L-Mesitran Soft was notably effective. Chronic wounds like this can persist due to infections and inflammation, severely impacting the patient’s quality of life. L-Mesitran Soft’s antimicrobial and pro-healing properties played a critical role in this case. The honey-based ointment prevented infections through multiple mechanisms, including its low pH, osmotic action, and hydrogen peroxide production. These properties, combined with the vitamins in L-Mesitran, provided superior anti-biofilm activity and prevented new infections by forming a protective barrier over the wound.

Additionally, the ointment’s ability to keep the wound moist facilitated healing, stimulated blood flow, and promoted autolytic debridement. The reduced oxidative and inflammatory stress created a conducive environment for tissue regeneration, promoting angiogenesis and reepithelialization.

Conclusion: This case demonstrates the effectiveness of L-Mesitran Soft in treating chronic wounds where other treatments had failed. Its strong antimicrobial and healing properties make it a promising therapy that can complement or replace traditional antibiotics. The patient’s successful recovery underscores the potential of medical-grade honey in managing and healing chronic wounds.

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