Successful Treatment of Pseudomonas aeruginosa Infected Wound in an Obese Patient

Product: L-Mesitran Ointment

Case study done by: Milias K , Nikolaidis D, Karamanlidis A,
Anastasiadis H, Vakalis I, Anemoulis P; surgeons at the 424 Military Hospital, Thessaloniki, Greece.


The case of a 43-year-old male patient with a severe wound infection caused by Pseudomonas aeruginosa has been successfully treated with the use of honey-based products. This patient had a history of pathogenic obesity, and his BMI had reduced to 33.9 after undergoing gall-pancreas diversion with pylorus preservation surgery.


The wound was initially stitched up, but it produced malodour and green exudate from the first night of post-op. Lab testing confirmed that the exudate was infected with Pseudomonas aeruginosa, and the wound had fully split open by the 5th day of post-op. By the 9th day, the wound was intensely malodorous and discharging pus. The wound’s dimensions were approximately 30 x 12 x 4 cm.

The patient was then treated with L-Mesitran Ointment. After 20 days of the honey-dressings application, the L-Mesitran Net was replaced with a collagen dressing for quicker healing. The L-Mesitran Ointment was continued to treat the wound. Since the third day of the treatment, the malodour disappeared, and the green exudate was no longer present. A lab-tested sample was negative to Pseudomonas aeruginosa. Gradually, the pus exudate was reduced, and the wound’s healing was promoted quickly with the use of the L-Mesitran Ointment in combination with net and collagen dressings.

After 28 days of combined treatment, the wound could be sutured again successfully. Four weeks later, the wound was almost completely healed.

The use of honey-based products for wound treatment is not a new concept. Honey has been known since antiquity as an efficient wound-healing product. Its development today, combined with present technology and therapeutics, has been shown to be very effective. The use of L-Mesitran Ointment has been found to be highly effective in the management of wound infections.

What defines obesity?

Obesity is a medical condition characterized by excessive accumulation of body fat that can have a negative impact on an individual’s health. It is typically defined as having a body mass index (BMI) of 30 or higher. BMI is calculated by dividing an individual’s weight in kilograms by their height in meters squared.

Obesity is considered a chronic disease and is associated with a wide range of health problems, including type 2 diabetes, cardiovascular disease, high blood pressure, sleep apnea, joint problems, and certain types of cancer. It can also have psychological effects, such as low self-esteem, depression, and anxiety.

Obesity can result from a combination of genetic, environmental, and behavioral factors, such as a diet high in calories and fat, a sedentary lifestyle, and genetic predisposition. Treatment for obesity may include changes in diet and exercise, behavioral therapy, medication, or in severe cases, surgery.

What is Pseudomonas aeruginosa?

Pseudomonas aeruginosa is a Gram-negative, rod-shaped bacterium that is commonly found in soil, water, and other moist environments. It is an opportunistic pathogen, meaning that it can cause infections in people with weakened immune systems, such as those with cystic fibrosis, HIV/AIDS, or undergoing chemotherapy.

Pseudomonas aeruginosa

P. aeruginosa infections can range from minor skin infections to severe systemic infections, such as pneumonia, sepsis, and urinary tract infections. It is also a common cause of infections in hospitals and other healthcare settings, especially in patients with indwelling medical devices such as catheters and ventilators.

This bacteria can develop resistance to common antibiotics and therefore treatin it can be very hard. Treatment may involve the use of combination therapy with multiple of these antibiotics or the use of alternative therapies, such as phage therapy or immunotherapy. Moreover, Medical Grade Honey is a promising potent novel therapy.

Preventing P. aeruginosa infections involves good hygiene practices, such as hand washing and regular cleaning and disinfection of surfaces, as well as avoiding exposure to contaminated water and soil.